Nurse Practitioner Salary in Chicago, IL
Nurse Practitioners in Chicago, IL earn a median of $115,000/year, ranging from $89,000 (25th percentile) to $178,000 (90th percentile). After Illinois state taxes (4.95%) and cost-of-living adjustments (COL index 107), this is equivalent to $107,477 in purchasing power vs the US average.
On the ground in Chicago, IL
Nurse practitioners in this market draw from a wide pool of regional employers. Notable employers in this market include Northwestern Medicine, Rush, Advocate Aurora Health, and UChicago Medicine, with smaller specialty practices and clinic networks rounding out the demand. Median pay lands roughly $115K to $145K, and a two-bedroom in Lincoln Park or Pilsen runs $2,400 to $2,900 monthly. Most workers commute via the CTA Red and Blue lines, plus Metra commuter rail from the suburbs, which shapes where it makes sense to live relative to where you work. Factor in the 4.95% flat state income tax when sizing up offers against no-tax states. Day-to-day, long winters where wind chill matters more than the thermometer influences whether you plan around parking, transit passes, or just the seasons themselves.
1Salary Distribution in Chicago, IL
2Estimated Take-Home & Purchasing Power
* Estimates only. Does not include federal income tax, 401k, health insurance, or local taxes. Use the Salary Calculator for a detailed breakdown.
How Does Chicago, IL Compare?
| City | Median | COL Index | COL-Adjusted |
|---|---|---|---|
| Chicago, IL (current) | $115,000 | 107 | $107,477 |
| San Francisco, CA | $155,000 | 186 | $83,333 |
| New York, NY | $135,000 | 187 | $72,193 |
| Seattle, WA | $145,000 | 162 | $89,506 |
| Boston, MA | $138,000 | 162 | $85,185 |
| Austin, TX | $118,000 | 124 | $95,161 |
4Frequently Asked Questions
What is the average Nurse Practitioner salary in Chicago, IL?
The median Nurse Practitioner salary in Chicago, IL is $115,000 per year as of 2026 BLS OEWS data. The 25th percentile is $89,000 and the 90th percentile is $178,000.
Is Chicago, IL a good place to work as a Nurse Practitioner?
Chicago, IL has a cost of living index of 107 (US average = 100). After adjusting for cost of living, a $115,000 Nurse Practitioner salary in Chicago, IL is equivalent to $107,477 in purchasing power compared to the US average.
What is the cost of living adjustment for Chicago, IL?
Chicago, IL has a cost of living index of 107, meaning it is 7% more expensive than the US average. The state income tax rate in Illinois is approximately 4.95%.
What is the Nurse Practitioner salary range in Chicago, IL?
In Chicago, IL, Nurse Practitioners earn between $89,000 (25th percentile) and $178,000 (90th percentile), with a median of $115,000 per year.
How many Nurse Practitioner jobs are there in Chicago, IL?
According to BLS OEWS data, there are approximately 10,000 Nurse Practitioner positions in the Chicago, IL metropolitan area.
What do Nurse Practitioners earn in Chicago, IL?
Based on BLS OEWS 2026 data, Nurse Practitioners in Chicago, IL earn a median annual wage of $115,000. The middle 50% earn between $89,000 and $147,000. The top 10% earn more than $178,000. There are approximately 10,000 Nurse Practitioners employed in the Chicago, IL metro area, with annual job growth estimated at 4%.
Is Chicago, IL a good place for a Nurse Practitioner?
Chicago, IL has a cost of living index of 107 (US average = 100), making it 7% more expensive than the national average. After adjusting for cost of living, a Nurse Practitioner in Chicago, IL earning $115,000has the equivalent purchasing power of $107,477 relative to the US median. Illinois has a state income tax rate of approximately 4.95%.
What is the cost of living adjustment for Chicago, IL?
Chicago, IL's cost of living index is 107, based on composite data including housing, food, transportation, healthcare, and utilities. This means that $115,000 in Chicago, ILhas the same purchasing power as $107,477 in a city at exactly the US average cost of living. Housing is typically the largest driver of cost of living differences between metros.
Compare Chicago, IL with Another City
See a detailed side-by-side comparison of salary, taxes, and purchasing power.
5Should You Work as a Nurse Practitioner in Chicago, IL?
The headline median of $115,000 is only part of the picture. Chicago, IL's cost of living index is 107 (US average = 100), meaning a dollar here buys roughly 93¢ of what it buys in an average US city. The $115,000 salary effectively purchases $107,477 worth of goods and services at national-average prices.
Housing is the single biggest driver of cost-of-living differences between metros. In Chicago, IL, housing costs fall closer to the national average of 25–30% of gross income, leaving more room in the budget for savings, transportation, and discretionary spending. For a $115,000 salary, that translates to roughly $32,200/year on housing alone.
State tax plays a meaningful but smaller role. Illinois levies a state income tax of approximately 4.95%, which reduces take-home by roughly $5,693 per year on this salary. States with zero income tax (Texas, Florida, Washington, Tennessee, Nevada) offer a structural advantage, but often offset it with higher sales tax or property tax. After state tax and approximate federal FICA (~7.6%), the estimated take-home is $101,000. This excludes federal income tax, which varies by filing status and deductions.
For comparison, here are nearby alternatives: San Francisco, CA ($155,000 median, COL 186); New York, NY ($135,000 median, COL 187); Seattle, WA ($145,000 median, COL 162). If you're optimizing for purchasing power, compare the COL-adjusted column in the table above and pick the highest number. If you're optimizing for career progression, weight total employment and yearly growth in the role — larger markets offer more lateral moves and promotion velocity, even when nominal pay is lower.
The 4% year-over-year growth rate for Nurse Practitioners in Chicago, IL is a leading indicator of market health. Healthy growth at a steady pace — enough to support mobility but not so fast that compensation is racing ahead of credentials. For side-by-side comparisons, try the full city ranking for Nurse Practitioners or the Illinois state overview.
Data source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS) Program. All figures are approximate annual estimates based on the most recent available BLS data. Actual salaries may vary based on experience, education, employer size, and specific role. Cost-of-living data represents composite indices from publicly available metropolitan area data.