SalariesByCity
Physician · Salary Comparison · 2026

Physician Salary: Houston, TX vs San Francisco, CA

Side-by-side comparison of salary, taxes, cost of living, and take-home pay for Physicians in Houston, TX and San Francisco, CA, based on BLS OEWS 2026 data.

1Which City Pays More After Tax?

Higher Gross Salary
San Francisco, CA
$220,000 vs $260,000
Better Purchasing Power
Houston, TX
$205,607 vs $139,785
Best Take-Home (COL-Adj)
Houston, TX
$189,981 vs $117,149
2

Detailed Comparison

MetricHouston, TXSan Francisco, CADiff
Median Annual Salary$220,000$260,000-$40,000
25th Percentile$165,000$195,000-$30,000
75th Percentile$288,000$340,000-$52,000
90th Percentile$358,000$420,000-$62,000
Cost of Living Index107186-79
State Income Tax0%9.3%-9.3%
COL-Adjusted Median$205,607$139,785+$65,822
Est. Annual Take-Home$203,280$217,898-$14,618
COL-Adj. Take-Home$189,981$117,149+$72,832
Total Employment14,0008,000+6,000
▲ = Higher value wins for this metric. Diff = Houston, TX minus San Francisco, CA.

3Summary Analysis

On paper, San Francisco, CA pays $40,000 more (median: $220,000 vs $260,000). However, after adjusting for cost of living (index 107 vs 186), Houston, TX provides better purchasing power ($205,607 vs $139,785 equivalent). Houston, TX has no state income tax, which is a significant advantage.

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Data: U.S. Bureau of Labor Statistics OEWS · 2026 · Cost-of-living indices from composite metro area data. Take-home estimates approximate only — consult a tax professional for accurate figures.