SalariesByCity
Physician · Salary Comparison · 2026

Physician Salary: San Francisco, CA vs Houston, TX

Side-by-side comparison of salary, taxes, cost of living, and take-home pay for Physicians in San Francisco, CA and Houston, TX, based on BLS OEWS 2026 data.

1Which City Pays More After Tax?

Higher Gross Salary
San Francisco, CA
$260,000 vs $220,000
Better Purchasing Power
Houston, TX
$139,785 vs $205,607
Best Take-Home (COL-Adj)
Houston, TX
$117,149 vs $189,981
2

Detailed Comparison

MetricSan Francisco, CAHouston, TXDiff
Median Annual Salary$260,000$220,000+$40,000
25th Percentile$195,000$165,000+$30,000
75th Percentile$340,000$288,000+$52,000
90th Percentile$420,000$358,000+$62,000
Cost of Living Index186107+79
State Income Tax9.3%0%+9.3%
COL-Adjusted Median$139,785$205,607-$65,822
Est. Annual Take-Home$217,898$203,280+$14,618
COL-Adj. Take-Home$117,149$189,981-$72,832
Total Employment8,00014,000-6,000
▲ = Higher value wins for this metric. Diff = San Francisco, CA minus Houston, TX.

3Summary Analysis

On paper, San Francisco, CA pays $40,000 more (median: $260,000 vs $220,000). However, after adjusting for cost of living (index 186 vs 107), Houston, TX provides better purchasing power ($139,785 vs $205,607 equivalent). Houston, TX has no state income tax, which is a significant advantage.

Data: U.S. Bureau of Labor Statistics OEWS · 2026 · Cost-of-living indices from composite metro area data. Take-home estimates approximate only — consult a tax professional for accurate figures.