SalariesByCity
Nurse Practitioner · Salary Comparison · 2026

Nurse Practitioner Salary: Indianapolis, IN vs New York, NY

Side-by-side comparison of salary, taxes, cost of living, and take-home pay for Nurse Practitioners in Indianapolis, IN and New York, NY, based on BLS OEWS 2026 data.

1Which City Pays More After Tax?

Higher Gross Salary
New York, NY
$95,000 vs $135,000
Better Purchasing Power
Indianapolis, IN
$105,556 vs $72,193
Best Take-Home (COL-Adj)
Indianapolis, IN
$94,461 vs $62,136
2

Detailed Comparison

MetricIndianapolis, INNew York, NYDiff
Median Annual Salary$95,000$135,000-$40,000
25th Percentile$73,000$104,000-$31,000
75th Percentile$122,000$173,000-$51,000
90th Percentile$148,000$210,000-$62,000
Cost of Living Index90187-97
State Income Tax3.15%6.85%-3.6999999999999997%
COL-Adjusted Median$105,556$72,193+$33,363
Est. Annual Take-Home$85,015$116,195-$31,180
COL-Adj. Take-Home$94,461$62,136+$32,325
Total Employment5,00014,000-9,000
▲ = Higher value wins for this metric. Diff = Indianapolis, IN minus New York, NY.

3Summary Analysis

On paper, New York, NY pays $40,000 more (median: $95,000 vs $135,000). However, after adjusting for cost of living (index 90 vs 187), Indianapolis, IN provides better purchasing power ($105,556 vs $72,193 equivalent). Indianapolis, IN has the lower state tax rate (3.15% vs 6.85%).

Data: U.S. Bureau of Labor Statistics OEWS · 2026 · Cost-of-living indices from composite metro area data. Take-home estimates approximate only — consult a tax professional for accurate figures.