SalariesByCity
Medical Assistant · Salary Comparison · 2026

Medical Assistant Salary: Seattle, WA vs San Francisco, CA

Side-by-side comparison of salary, taxes, cost of living, and take-home pay for Medical Assistants in Seattle, WA and San Francisco, CA, based on BLS OEWS 2026 data.

1Which City Pays More After Tax?

Higher Gross Salary
San Francisco, CA
$51,000 vs $53,000
Better Purchasing Power
Seattle, WA
$31,481 vs $28,495
Best Take-Home (COL-Adj)
Seattle, WA
$29,089 vs $23,881
2

Detailed Comparison

MetricSeattle, WASan Francisco, CADiff
Median Annual Salary$51,000$53,000-$2,000
25th Percentile$39,270$40,810-$1,540
75th Percentile$65,280$67,840-$2,560
90th Percentile$81,600$84,800-$3,200
Cost of Living Index162186-24
State Income Tax0%9.3%-9.3%
COL-Adjusted Median$31,481$28,495+$2,986
Est. Annual Take-Home$47,124$44,418+$2,706
COL-Adj. Take-Home$29,089$23,881+$5,208
Total Employment145,000130,000+15,000
▲ = Higher value wins for this metric. Diff = Seattle, WA minus San Francisco, CA.

3Summary Analysis

On paper, San Francisco, CA pays $2,000 more (median: $51,000 vs $53,000). However, after adjusting for cost of living (index 162 vs 186), Seattle, WA provides better purchasing power ($31,481 vs $28,495 equivalent). Seattle, WA has no state income tax, which is a significant advantage.

Data: U.S. Bureau of Labor Statistics OEWS · 2026 · Cost-of-living indices from composite metro area data. Take-home estimates approximate only — consult a tax professional for accurate figures.