SalariesByCity
Medical Assistant · Salary Comparison · 2026

Medical Assistant Salary: San Francisco, CA vs Seattle, WA

Side-by-side comparison of salary, taxes, cost of living, and take-home pay for Medical Assistants in San Francisco, CA and Seattle, WA, based on BLS OEWS 2026 data.

1Which City Pays More After Tax?

Higher Gross Salary
San Francisco, CA
$53,000 vs $51,000
Better Purchasing Power
Seattle, WA
$28,495 vs $31,481
Best Take-Home (COL-Adj)
Seattle, WA
$23,881 vs $29,089
2

Detailed Comparison

MetricSan Francisco, CASeattle, WADiff
Median Annual Salary$53,000$51,000+$2,000
25th Percentile$40,810$39,270+$1,540
75th Percentile$67,840$65,280+$2,560
90th Percentile$84,800$81,600+$3,200
Cost of Living Index186162+24
State Income Tax9.3%0%+9.3%
COL-Adjusted Median$28,495$31,481-$2,986
Est. Annual Take-Home$44,418$47,124-$2,706
COL-Adj. Take-Home$23,881$29,089-$5,208
Total Employment130,000145,000-15,000
▲ = Higher value wins for this metric. Diff = San Francisco, CA minus Seattle, WA.

3Summary Analysis

On paper, San Francisco, CA pays $2,000 more (median: $53,000 vs $51,000). However, after adjusting for cost of living (index 186 vs 162), Seattle, WA provides better purchasing power ($28,495 vs $31,481 equivalent). Seattle, WA has no state income tax, which is a significant advantage.

Data: U.S. Bureau of Labor Statistics OEWS · 2026 · Cost-of-living indices from composite metro area data. Take-home estimates approximate only — consult a tax professional for accurate figures.