SalariesByCity
Medical Assistant · Salary Comparison · 2026

Medical Assistant Salary: San Diego, CA vs New York, NY

Side-by-side comparison of salary, taxes, cost of living, and take-home pay for Medical Assistants in San Diego, CA and New York, NY, based on BLS OEWS 2026 data.

1Which City Pays More After Tax?

Higher Gross Salary
New York, NY
$44,000 vs $50,000
Better Purchasing Power
San Diego, CA
$28,947 vs $26,738
Best Take-Home (COL-Adj)
San Diego, CA
$24,260 vs $23,013
2

Detailed Comparison

MetricSan Diego, CANew York, NYDiff
Median Annual Salary$44,000$50,000-$6,000
25th Percentile$33,880$38,500-$4,620
75th Percentile$56,320$64,000-$7,680
90th Percentile$70,400$80,000-$9,600
Cost of Living Index152187-35
State Income Tax9.3%6.85%+2.450000000000001%
COL-Adjusted Median$28,947$26,738+$2,209
Est. Annual Take-Home$36,875$43,035-$6,160
COL-Adj. Take-Home$24,260$23,013+$1,247
Total Employment60,000170,000-110,000
▲ = Higher value wins for this metric. Diff = San Diego, CA minus New York, NY.

3Summary Analysis

On paper, New York, NY pays $6,000 more (median: $44,000 vs $50,000). However, after adjusting for cost of living (index 152 vs 187), San Diego, CA provides better purchasing power ($28,947 vs $26,738 equivalent). New York, NY has the lower state tax rate (6.85% vs 9.3%).

Data: U.S. Bureau of Labor Statistics OEWS · 2026 · Cost-of-living indices from composite metro area data. Take-home estimates approximate only — consult a tax professional for accurate figures.