SalariesByCity
Medical Assistant · Salary Comparison · BLS OEWS May 2025

Medical Assistant Salary: Indianapolis, IN vs San Francisco, CA

Side-by-side comparison of wages and local price levels for Medical Assistants in Indianapolis, IN and San Francisco, CA, based on BLS OEWS May 2025 wage data and BEA regional price parities for 2024.

1Which City Pays More?

Higher Median Wage
✓ San Francisco, CA
$46,900 vs $59,790
Higher at National-Average Prices
✓ San Francisco, CA
$49,009 vs $51,716
2

Detailed Comparison

MetricIndianapolis, INSan Francisco, CADiff
Median Annual Salary$46,900$59,790▲-$12,890
25th Percentile$40,200$50,120▲-$9,920
75th Percentile$47,680$77,260▲-$29,580
90th Percentile$56,430$79,750▲-$23,320
Price Level (BEA 2024, US = 100)95.7115.6-19.9
Median at National-Average Prices$49,009$51,716▲-$2,707
Total Employment6,58014,320-7,740
▲ = Higher value wins for this metric. Diff = Indianapolis, IN minus San Francisco, CA.

3Summary Analysis

On paper, San Francisco, CA pays $12,890 more (median: $46,900 vs $59,790). BEA's regional price parity is 95.7 in Indianapolis, IN and 115.6 in San Francisco, CA (United States = 100). At national-average prices the medians are $49,009 and $51,716, so San Francisco, CA comes out ahead once local prices are counted.

5Reading This Comparison

The $12,890 gap between the two medians is a gap in dollars, not in what those dollars buy. Dividing each median by its area's regional price parity restates it at national-average prices: $49,009 for Indianapolis and $51,716 for San Francisco, a difference of $2,707.

The price levels come from the U.S. Bureau of Economic Analysis, which describes them this way: “Regional price parities (RPPs) measure the differences in price levels across states and metropolitan areas for a given year and are expressed as a percentage of the overall national price level.” The figures used here are the all-items index for each whole metropolitan area (Indianapolis-Carmel-Greenwood, IN; San Francisco-Oakland-Fremont, CA) and cover prices only, not taxes.

BLS estimates 6,580 Medical Assistant jobs in the Indianapolis area and 14,320 in the San Francisco area. For broader context, see our Indiana overview and the full Medical Assistant city ranking.

Frequently Asked Questions

Is Medical Assistant salary higher in Indianapolis, IN or San Francisco, CA?

San Francisco, CA has the higher median wage for Medical Assistants ($59,790 per year, against $46,900 in Indianapolis, IN; BLS OEWS May 2025). Restated at national-average prices using BEA regional price parities, the medians are $49,009 in Indianapolis, IN and $51,716 in San Francisco, CA.

How do prices compare between Indianapolis, IN and San Francisco, CA?

The U.S. Bureau of Economic Analysis puts the 2024 regional price parity at 95.7 for the Indianapolis-Carmel-Greenwood, IN metropolitan area and 115.6 for the San Francisco-Oakland-Fremont, CA metropolitan area, where the United States is 100. That is 4.3% below the national level for Indianapolis, IN and 15.6% above the national level for San Francisco, CA.

Which city pays Medical Assistants more once local prices are counted?

San Francisco, CA: at national-average prices its median Medical Assistant wage is $51,716, against $49,009 for Indianapolis, IN. The adjustment divides each median by the area's BEA regional price parity and covers prices only, not taxes.

Wages and employment: U.S. Bureau of Labor Statistics, OEWS May 2025. Price levels: U.S. Bureau of Economic Analysis, regional price parities (all items) for 2024, tables last updated February 19, 2026.