SalariesByCity
Medical Assistant · Salary Comparison · 2026

Medical Assistant Salary: Denver, CO vs Boston, MA

Side-by-side comparison of salary, taxes, cost of living, and take-home pay for Medical Assistants in Denver, CO and Boston, MA, based on BLS OEWS 2026 data.

1Which City Pays More After Tax?

Higher Gross Salary
Boston, MA
$41,000 vs $47,000
Better Purchasing Power
Denver, CO
$32,031 vs $29,012
Best Take-Home (COL-Adj)
Denver, CO
$28,295 vs $25,467
2

Detailed Comparison

MetricDenver, COBoston, MADiff
Median Annual Salary$41,000$47,000-$6,000
25th Percentile$31,570$36,190-$4,620
75th Percentile$52,480$60,160-$7,680
90th Percentile$65,600$75,200-$9,600
Cost of Living Index128162-34
State Income Tax4.4%5%-0.5999999999999996%
COL-Adjusted Median$32,031$29,012+$3,019
Est. Annual Take-Home$36,217$41,257-$5,040
COL-Adj. Take-Home$28,295$25,467+$2,828
Total Employment70,000105,000-35,000
▲ = Higher value wins for this metric. Diff = Denver, CO minus Boston, MA.

3Summary Analysis

On paper, Boston, MA pays $6,000 more (median: $41,000 vs $47,000). However, after adjusting for cost of living (index 128 vs 162), Denver, CO provides better purchasing power ($32,031 vs $29,012 equivalent). Denver, CO has the lower state tax rate (4.4% vs 5%).

Data: U.S. Bureau of Labor Statistics OEWS · 2026 · Cost-of-living indices from composite metro area data. Take-home estimates approximate only — consult a tax professional for accurate figures.