SalariesByCity
Medical Assistant · Salary Comparison · 2026

Medical Assistant Salary: Chicago, IL vs New York, NY

Side-by-side comparison of salary, taxes, cost of living, and take-home pay for Medical Assistants in Chicago, IL and New York, NY, based on BLS OEWS 2026 data.

1Which City Pays More After Tax?

Higher Gross Salary
New York, NY
$38,000 vs $50,000
Better Purchasing Power
Chicago, IL
$35,514 vs $26,738
Best Take-Home (COL-Adj)
Chicago, IL
$31,191 vs $23,013
2

Detailed Comparison

MetricChicago, ILNew York, NYDiff
Median Annual Salary$38,000$50,000-$12,000
25th Percentile$29,260$38,500-$9,240
75th Percentile$48,640$64,000-$15,360
90th Percentile$60,800$80,000-$19,200
Cost of Living Index107187-80
State Income Tax4.95%6.85%-1.8999999999999995%
COL-Adjusted Median$35,514$26,738+$8,776
Est. Annual Take-Home$33,374$43,035-$9,661
COL-Adj. Take-Home$31,191$23,013+$8,178
Total Employment87,500170,000-82,500
▲ = Higher value wins for this metric. Diff = Chicago, IL minus New York, NY.

3Summary Analysis

On paper, New York, NY pays $12,000 more (median: $38,000 vs $50,000). However, after adjusting for cost of living (index 107 vs 187), Chicago, IL provides better purchasing power ($35,514 vs $26,738 equivalent). Chicago, IL has the lower state tax rate (4.95% vs 6.85%).

Data: U.S. Bureau of Labor Statistics OEWS · 2026 · Cost-of-living indices from composite metro area data. Take-home estimates approximate only — consult a tax professional for accurate figures.