SalariesByCity
Machine Learning Engineer · Salary Comparison · 2026

Machine Learning Engineer Salary: Louisville, KY vs San Francisco, CA

Side-by-side comparison of salary, taxes, cost of living, and take-home pay for Machine Learning Engineers in Louisville, KY and San Francisco, CA, based on BLS OEWS 2026 data.

1Which City Pays More After Tax?

Higher Gross Salary
San Francisco, CA
$97,000 vs $170,000
Better Purchasing Power
Louisville, KY
$111,494 vs $91,398
Best Take-Home (COL-Adj)
Louisville, KY
$98,900 vs $76,598
2

Detailed Comparison

MetricLouisville, KYSan Francisco, CADiff
Median Annual Salary$97,000$170,000-$73,000
25th Percentile$74,690$130,900-$56,210
75th Percentile$124,160$217,600-$93,440
90th Percentile$155,200$272,000-$116,800
Cost of Living Index87186-99
State Income Tax4%9.3%-5.300000000000001%
COL-Adjusted Median$111,494$91,398+$20,096
Est. Annual Take-Home$86,043$142,472-$56,429
COL-Adj. Take-Home$98,900$76,598+$22,302
Total Employment8,00041,600-33,600
▲ = Higher value wins for this metric. Diff = Louisville, KY minus San Francisco, CA.

3Summary Analysis

On paper, San Francisco, CA pays $73,000 more (median: $97,000 vs $170,000). However, after adjusting for cost of living (index 87 vs 186), Louisville, KY provides better purchasing power ($111,494 vs $91,398 equivalent). Louisville, KY has the lower state tax rate (4% vs 9.3%).

Data: U.S. Bureau of Labor Statistics OEWS · 2026 · Cost-of-living indices from composite metro area data. Take-home estimates approximate only — consult a tax professional for accurate figures.