SalariesByCity
Registered Nurse · Salary Comparison · BLS OEWS May 2025

Registered Nurse Salary: San Francisco, CA vs Denver, CO

Side-by-side comparison of wages and local price levels for Registered Nurses in San Francisco, CA and Denver, CO, based on BLS OEWS May 2025 wage data and BEA regional price parities for 2024.

1Which City Pays More?

Higher Median Wage
✓ San Francisco, CA
$186,610 vs $101,130
Higher at National-Average Prices
✓ San Francisco, CA
$161,409 vs $95,602
2

Detailed Comparison

MetricSan Francisco, CADenver, CODiff
Median Annual Salary$186,610▲$101,130+$85,480
25th Percentile$137,120▲$85,390+$51,730
75th Percentile$215,630▲$109,760+$105,870
90th Percentile$223,770▲$125,870+$97,900
Price Level (BEA 2024, US = 100)115.6105.8+9.8
Median at National-Average Prices$161,409▲$95,602+$65,807
Total Employment41,75030,380+11,370
▲ = Higher value wins for this metric. Diff = San Francisco, CA minus Denver, CO.

3Summary Analysis

On paper, San Francisco, CA pays $85,480 more (median: $186,610 vs $101,130). BEA's regional price parity is 115.6 in San Francisco, CA and 105.8 in Denver, CO (United States = 100). At national-average prices the medians are $161,409 and $95,602, so San Francisco, CA comes out ahead once local prices are counted.

5Reading This Comparison

The $85,480 gap between the two medians is a gap in dollars, not in what those dollars buy. Dividing each median by its area's regional price parity restates it at national-average prices: $161,409 for San Francisco and $95,602 for Denver, a difference of $65,807.

The price levels come from the U.S. Bureau of Economic Analysis, which describes them this way: “Regional price parities (RPPs) measure the differences in price levels across states and metropolitan areas for a given year and are expressed as a percentage of the overall national price level.” The figures used here are the all-items index for each whole metropolitan area (San Francisco-Oakland-Fremont, CA; Denver-Aurora-Centennial, CO) and cover prices only, not taxes.

BLS estimates 41,750 Registered Nurse jobs in the San Francisco area and 30,380 in the Denver area. For broader context, see our California overview and the full Registered Nurse city ranking.

Frequently Asked Questions

Is Registered Nurse salary higher in San Francisco, CA or Denver, CO?

San Francisco, CA has the higher median wage for Registered Nurses ($186,610 per year, against $101,130 in Denver, CO; BLS OEWS May 2025). Restated at national-average prices using BEA regional price parities, the medians are $161,409 in San Francisco, CA and $95,602 in Denver, CO.

How do prices compare between San Francisco, CA and Denver, CO?

The U.S. Bureau of Economic Analysis puts the 2024 regional price parity at 115.6 for the San Francisco-Oakland-Fremont, CA metropolitan area and 105.8 for the Denver-Aurora-Centennial, CO metropolitan area, where the United States is 100. That is 15.6% above the national level for San Francisco, CA and 5.8% above the national level for Denver, CO.

Which city pays Registered Nurses more once local prices are counted?

San Francisco, CA: at national-average prices its median Registered Nurse wage is $161,409, against $95,602 for Denver, CO. The adjustment divides each median by the area's BEA regional price parity and covers prices only, not taxes.

Wages and employment: U.S. Bureau of Labor Statistics, OEWS May 2025. Price levels: U.S. Bureau of Economic Analysis, regional price parities (all items) for 2024, tables last updated February 19, 2026.