SalariesByCity
Registered Nurse · Salary Comparison · BLS OEWS May 2025

Registered Nurse Salary: San Francisco, CA vs Boston, MA

Side-by-side comparison of wages and local price levels for Registered Nurses in San Francisco, CA and Boston, MA, based on BLS OEWS May 2025 wage data and BEA regional price parities for 2024.

1Which City Pays More?

Higher Median Wage
✓ San Francisco, CA
$186,610 vs $106,180
Higher at National-Average Prices
✓ San Francisco, CA
$161,409 vs $98,073
2

Detailed Comparison

MetricSan Francisco, CABoston, MADiff
Median Annual Salary$186,610▲$106,180+$80,430
25th Percentile$137,120▲$94,870+$42,250
75th Percentile$215,630▲$153,380+$62,250
90th Percentile$223,770▲$188,670+$35,100
Price Level (BEA 2024, US = 100)115.6108.3+7.3
Median at National-Average Prices$161,409▲$98,073+$63,336
Total Employment41,75064,240-22,490
▲ = Higher value wins for this metric. Diff = San Francisco, CA minus Boston, MA.

3Summary Analysis

On paper, San Francisco, CA pays $80,430 more (median: $186,610 vs $106,180). BEA's regional price parity is 115.6 in San Francisco, CA and 108.3 in Boston, MA (United States = 100). At national-average prices the medians are $161,409 and $98,073, so San Francisco, CA comes out ahead once local prices are counted.

5Reading This Comparison

The $80,430 gap between the two medians is a gap in dollars, not in what those dollars buy. Dividing each median by its area's regional price parity restates it at national-average prices: $161,409 for San Francisco and $98,073 for Boston, a difference of $63,336.

The price levels come from the U.S. Bureau of Economic Analysis, which describes them this way: “Regional price parities (RPPs) measure the differences in price levels across states and metropolitan areas for a given year and are expressed as a percentage of the overall national price level.” The figures used here are the all-items index for each whole metropolitan area (San Francisco-Oakland-Fremont, CA; Boston-Cambridge-Newton, MA-NH) and cover prices only, not taxes.

BLS estimates 41,750 Registered Nurse jobs in the San Francisco area and 64,240 in the Boston area. For broader context, see our California overview and the full Registered Nurse city ranking.

Frequently Asked Questions

Is Registered Nurse salary higher in San Francisco, CA or Boston, MA?

San Francisco, CA has the higher median wage for Registered Nurses ($186,610 per year, against $106,180 in Boston, MA; BLS OEWS May 2025). Restated at national-average prices using BEA regional price parities, the medians are $161,409 in San Francisco, CA and $98,073 in Boston, MA.

How do prices compare between San Francisco, CA and Boston, MA?

The U.S. Bureau of Economic Analysis puts the 2024 regional price parity at 115.6 for the San Francisco-Oakland-Fremont, CA metropolitan area and 108.3 for the Boston-Cambridge-Newton, MA-NH metropolitan area, where the United States is 100. That is 15.6% above the national level for San Francisco, CA and 8.3% above the national level for Boston, MA.

Which city pays Registered Nurses more once local prices are counted?

San Francisco, CA: at national-average prices its median Registered Nurse wage is $161,409, against $98,073 for Boston, MA. The adjustment divides each median by the area's BEA regional price parity and covers prices only, not taxes.

Wages and employment: U.S. Bureau of Labor Statistics, OEWS May 2025. Price levels: U.S. Bureau of Economic Analysis, regional price parities (all items) for 2024, tables last updated February 19, 2026.