SalariesByCity
Registered Nurse · Salary Comparison · 2026

Registered Nurse Salary: San Diego, CA vs Boston, MA

Side-by-side comparison of salary, taxes, cost of living, and take-home pay for Registered Nurses in San Diego, CA and Boston, MA, based on BLS OEWS 2026 data.

1Which City Pays More After Tax?

Higher Gross Salary
San Diego, CA
$112,000 vs $108,000
Better Purchasing Power
San Diego, CA
$73,684 vs $66,667
Best Take-Home (COL-Adj)
San Diego, CA
$61,753 vs $58,520
2

Detailed Comparison

MetricSan Diego, CABoston, MADiff
Median Annual Salary$112,000$108,000+$4,000
25th Percentile$85,000$82,000+$3,000
75th Percentile$143,000$138,000+$5,000
90th Percentile$174,000$168,000+$6,000
Cost of Living Index152162-10
State Income Tax9.3%5%+4.300000000000001%
COL-Adjusted Median$73,684$66,667+$7,017
Est. Annual Take-Home$93,864$94,802-$938
COL-Adj. Take-Home$61,753$58,520+$3,233
Total Employment25,00038,000-13,000
▲ = Higher value wins for this metric. Diff = San Diego, CA minus Boston, MA.

3Summary Analysis

On paper, San Diego, CA pays $4,000 more (median: $112,000 vs $108,000). However, after adjusting for cost of living (index 152 vs 162), San Diego, CA provides better purchasing power ($73,684 vs $66,667 equivalent). Boston, MA has the lower state tax rate (5% vs 9.3%).

Data: U.S. Bureau of Labor Statistics OEWS · 2026 · Cost-of-living indices from composite metro area data. Take-home estimates approximate only — consult a tax professional for accurate figures.