SalariesByCity
Registered Nurse · Salary Comparison · BLS OEWS May 2025

Registered Nurse Salary: Detroit, MI vs San Francisco, CA

Side-by-side comparison of wages and local price levels for Registered Nurses in Detroit, MI and San Francisco, CA, based on BLS OEWS May 2025 wage data and BEA regional price parities for 2024.

1Which City Pays More?

Higher Median Wage
✓ San Francisco, CA
$97,280 vs $186,610
Higher at National-Average Prices
✓ San Francisco, CA
$96,991 vs $161,409
2

Detailed Comparison

MetricDetroit, MISan Francisco, CADiff
Median Annual Salary$97,280$186,610▲-$89,330
25th Percentile$82,470$137,120▲-$54,650
75th Percentile$104,150$215,630▲-$111,480
90th Percentile$110,650$223,770▲-$113,120
Price Level (BEA 2024, US = 100)100.3115.6-15.3
Median at National-Average Prices$96,991$161,409▲-$64,418
Total Employment44,31041,750+2,560
▲ = Higher value wins for this metric. Diff = Detroit, MI minus San Francisco, CA.

3Summary Analysis

On paper, San Francisco, CA pays $89,330 more (median: $97,280 vs $186,610). BEA's regional price parity is 100.3 in Detroit, MI and 115.6 in San Francisco, CA (United States = 100). At national-average prices the medians are $96,991 and $161,409, so San Francisco, CA comes out ahead once local prices are counted.

5Reading This Comparison

The $89,330 gap between the two medians is a gap in dollars, not in what those dollars buy. Dividing each median by its area's regional price parity restates it at national-average prices: $96,991 for Detroit and $161,409 for San Francisco, a difference of $64,418.

The price levels come from the U.S. Bureau of Economic Analysis, which describes them this way: “Regional price parities (RPPs) measure the differences in price levels across states and metropolitan areas for a given year and are expressed as a percentage of the overall national price level.” The figures used here are the all-items index for each whole metropolitan area (Detroit-Warren-Dearborn, MI; San Francisco-Oakland-Fremont, CA) and cover prices only, not taxes.

BLS estimates 44,310 Registered Nurse jobs in the Detroit area and 41,750 in the San Francisco area. For broader context, see our Michigan overview and the full Registered Nurse city ranking.

Frequently Asked Questions

Is Registered Nurse salary higher in Detroit, MI or San Francisco, CA?

San Francisco, CA has the higher median wage for Registered Nurses ($186,610 per year, against $97,280 in Detroit, MI; BLS OEWS May 2025). Restated at national-average prices using BEA regional price parities, the medians are $96,991 in Detroit, MI and $161,409 in San Francisco, CA.

How do prices compare between Detroit, MI and San Francisco, CA?

The U.S. Bureau of Economic Analysis puts the 2024 regional price parity at 100.3 for the Detroit-Warren-Dearborn, MI metropolitan area and 115.6 for the San Francisco-Oakland-Fremont, CA metropolitan area, where the United States is 100. That is 0.3% above the national level for Detroit, MI and 15.6% above the national level for San Francisco, CA.

Which city pays Registered Nurses more once local prices are counted?

San Francisco, CA: at national-average prices its median Registered Nurse wage is $161,409, against $96,991 for Detroit, MI. The adjustment divides each median by the area's BEA regional price parity and covers prices only, not taxes.

Wages and employment: U.S. Bureau of Labor Statistics, OEWS May 2025. Price levels: U.S. Bureau of Economic Analysis, regional price parities (all items) for 2024, tables last updated February 19, 2026.