SalariesByCity
Registered Nurse · Salary Comparison · 2026

Registered Nurse Salary: Chicago, IL vs Boston, MA

Side-by-side comparison of salary, taxes, cost of living, and take-home pay for Registered Nurses in Chicago, IL and Boston, MA, based on BLS OEWS 2026 data.

1Which City Pays More After Tax?

Higher Gross Salary
Boston, MA
$80,000 vs $108,000
Better Purchasing Power
Chicago, IL
$74,766 vs $66,667
Best Take-Home (COL-Adj)
Chicago, IL
$65,664 vs $58,520
2

Detailed Comparison

MetricChicago, ILBoston, MADiff
Median Annual Salary$80,000$108,000-$28,000
25th Percentile$62,000$82,000-$20,000
75th Percentile$102,000$138,000-$36,000
90th Percentile$124,000$168,000-$44,000
Cost of Living Index107162-55
State Income Tax4.95%5%-0.04999999999999982%
COL-Adjusted Median$74,766$66,667+$8,099
Est. Annual Take-Home$70,261$94,802-$24,541
COL-Adj. Take-Home$65,664$58,520+$7,144
Total Employment48,00038,000+10,000
▲ = Higher value wins for this metric. Diff = Chicago, IL minus Boston, MA.

3Summary Analysis

On paper, Boston, MA pays $28,000 more (median: $80,000 vs $108,000). However, after adjusting for cost of living (index 107 vs 162), Chicago, IL provides better purchasing power ($74,766 vs $66,667 equivalent). Chicago, IL has the lower state tax rate (4.95% vs 5%).

Data: U.S. Bureau of Labor Statistics OEWS · 2026 · Cost-of-living indices from composite metro area data. Take-home estimates approximate only — consult a tax professional for accurate figures.