SalariesByCity
Pharmacist · Salary Comparison · 2026

Pharmacist Salary: Columbus, OH vs San Francisco, CA

Side-by-side comparison of salary, taxes, cost of living, and take-home pay for Pharmacists in Columbus, OH and San Francisco, CA, based on BLS OEWS 2026 data.

1Which City Pays More After Tax?

Higher Gross Salary
San Francisco, CA
$81,000 vs $126,000
Better Purchasing Power
Columbus, OH
$89,011 vs $67,742
Best Take-Home (COL-Adj)
Columbus, OH
$78,965 vs $56,773
2

Detailed Comparison

MetricColumbus, OHSan Francisco, CADiff
Median Annual Salary$81,000$126,000-$45,000
25th Percentile$62,370$97,020-$34,650
75th Percentile$103,680$161,280-$57,600
90th Percentile$129,600$201,600-$72,000
Cost of Living Index91186-95
State Income Tax3.99%9.3%-5.3100000000000005%
COL-Adjusted Median$89,011$67,742+$21,269
Est. Annual Take-Home$71,858$105,597-$33,739
COL-Adj. Take-Home$78,965$56,773+$22,192
Total Employment12,80041,600-28,800
▲ = Higher value wins for this metric. Diff = Columbus, OH minus San Francisco, CA.

3Summary Analysis

On paper, San Francisco, CA pays $45,000 more (median: $81,000 vs $126,000). However, after adjusting for cost of living (index 91 vs 186), Columbus, OH provides better purchasing power ($89,011 vs $67,742 equivalent). Columbus, OH has the lower state tax rate (3.99% vs 9.3%).

Data: U.S. Bureau of Labor Statistics OEWS · 2026 · Cost-of-living indices from composite metro area data. Take-home estimates approximate only — consult a tax professional for accurate figures.