SalariesByCity
Medical Assistant · Salary Comparison · 2026

Medical Assistant Salary: Washington, DC vs San Francisco, CA

Side-by-side comparison of salary, taxes, cost of living, and take-home pay for Medical Assistants in Washington, DC and San Francisco, CA, based on BLS OEWS 2026 data.

1Which City Pays More After Tax?

Higher Gross Salary
San Francisco, CA
$46,000 vs $53,000
Better Purchasing Power
Washington, DC
$30,263 vs $28,495
Best Take-Home (COL-Adj)
Washington, DC
$26,145 vs $23,881
2

Detailed Comparison

MetricWashington, DCSan Francisco, CADiff
Median Annual Salary$46,000$53,000-$7,000
25th Percentile$35,420$40,810-$5,390
75th Percentile$58,880$67,840-$8,960
90th Percentile$73,600$84,800-$11,200
Cost of Living Index152186-34
State Income Tax6.5%9.3%-2.8000000000000007%
COL-Adjusted Median$30,263$28,495+$1,768
Est. Annual Take-Home$39,741$44,418-$4,677
COL-Adj. Take-Home$26,145$23,881+$2,264
Total Employment112,500130,000-17,500
▲ = Higher value wins for this metric. Diff = Washington, DC minus San Francisco, CA.

3Summary Analysis

On paper, San Francisco, CA pays $7,000 more (median: $46,000 vs $53,000). However, after adjusting for cost of living (index 152 vs 186), Washington, DC provides better purchasing power ($30,263 vs $28,495 equivalent). Washington, DC has the lower state tax rate (6.5% vs 9.3%).

Data: U.S. Bureau of Labor Statistics OEWS · 2026 · Cost-of-living indices from composite metro area data. Take-home estimates approximate only — consult a tax professional for accurate figures.