Medical Assistant · Salary Comparison · 2026
Medical Assistant Salary: Oklahoma City, OK vs San Francisco, CA
Side-by-side comparison of salary, taxes, cost of living, and take-home pay for Medical Assistants in Oklahoma City, OK and San Francisco, CA, based on BLS OEWS 2026 data.
1Which City Pays More After Tax?
Higher Gross Salary
✓ San Francisco, CA
$29,000 vs $53,000
Better Purchasing Power
✓ Oklahoma City, OK
$33,721 vs $28,495
Best Take-Home (COL-Adj)
✓ Oklahoma City, OK
$29,678 vs $23,881
2
Detailed Comparison
| Metric | Oklahoma City, OK | San Francisco, CA | Diff |
|---|---|---|---|
| Median Annual Salary | $29,000 | $53,000▲ | -$24,000 |
| 25th Percentile | $22,330 | $40,810▲ | -$18,480 |
| 75th Percentile | $37,120 | $67,840▲ | -$30,720 |
| 90th Percentile | $46,400 | $84,800▲ | -$38,400 |
| Cost of Living Index | 86 | 186 | -100 |
| State Income Tax | 4.75%▲ | 9.3% | -4.550000000000001% |
| COL-Adjusted Median | $33,721▲ | $28,495 | +$5,226 |
| Est. Annual Take-Home | $25,523 | $44,418▲ | -$18,895 |
| COL-Adj. Take-Home | $29,678▲ | $23,881 | +$5,797 |
| Total Employment | 22,500 | 130,000 | -107,500 |
▲ = Higher value wins for this metric. Diff = Oklahoma City, OK minus San Francisco, CA.
3Summary Analysis
On paper, San Francisco, CA pays $24,000 more (median: $29,000 vs $53,000). However, after adjusting for cost of living (index 86 vs 186), Oklahoma City, OK provides better purchasing power ($33,721 vs $28,495 equivalent). Oklahoma City, OK has the lower state tax rate (4.75% vs 9.3%).
Data: U.S. Bureau of Labor Statistics OEWS · 2026 · Cost-of-living indices from composite metro area data. Take-home estimates approximate only — consult a tax professional for accurate figures.