SalariesByCity
Data Scientist · Salary Comparison · 2026

Data Scientist Salary: San Francisco, CA vs Boston, MA

Side-by-side comparison of salary, taxes, cost of living, and take-home pay for Data Scientists in San Francisco, CA and Boston, MA, based on BLS OEWS 2026 data.

1Which City Pays More After Tax?

Higher Gross Salary
San Francisco, CA
$165,000 vs $148,000
Better Purchasing Power
Boston, MA
$88,710 vs $91,358
Best Take-Home (COL-Adj)
Boston, MA
$74,345 vs $80,194
2

Detailed Comparison

MetricSan Francisco, CABoston, MADiff
Median Annual Salary$165,000$148,000+$17,000
25th Percentile$125,000$112,000+$13,000
75th Percentile$215,000$192,000+$23,000
90th Percentile$270,000$240,000+$30,000
Cost of Living Index186162+24
State Income Tax9.3%5%+4.300000000000001%
COL-Adjusted Median$88,710$91,358-$2,648
Est. Annual Take-Home$138,281$129,914+$8,367
COL-Adj. Take-Home$74,345$80,194-$5,849
Total Employment18,00014,000+4,000
▲ = Higher value wins for this metric. Diff = San Francisco, CA minus Boston, MA.

3Summary Analysis

On paper, San Francisco, CA pays $17,000 more (median: $165,000 vs $148,000). However, after adjusting for cost of living (index 186 vs 162), Boston, MA provides better purchasing power ($88,710 vs $91,358 equivalent). Boston, MA has the lower state tax rate (5% vs 9.3%).

Data: U.S. Bureau of Labor Statistics OEWS · 2026 · Cost-of-living indices from composite metro area data. Take-home estimates approximate only — consult a tax professional for accurate figures.