Registered Nurse salary in South Carolina

The median annual wage for registered nurses in South Carolina is $82,360, according to the U.S. Bureau of Labor Statistics OEWS May 2025 estimates — below the national median of $97,550. South Carolina ranks 39 of 50 states and DC with published data for this occupation.

Median

$82,360

25th percentile

$77,320

75th percentile

$97,230

90th percentile

$106,520

Employment and national comparison

Employment in South Carolina	49,750
Mean annual wage in South Carolina	$87,670
National median	$97,550
National employment	3,379,720

States with similar pay for registered nurses

Ohio: median $82,510
Oklahoma: median $82,920
Missouri: median $81,780
Tennessee: median $81,500
Indiana: median $83,500
Kentucky: median $81,040

See all states ranked for registered nurses.

Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 estimates; state, metropolitan area and national files from https://www.bls.gov/oes/tables.htm. State estimates are for BLS occupation "Registered Nurses" (29-1141), cross-industry, all ownerships. Retrieved 2026-10-02. Where BLS does not publish a numeric estimate (suppressed, or reported only as at or above $239,200) the value is shown as —.